Yes. A quick estimate before or after the exact calculation can be an effective error check, especially when the numbers are large.

Estimation gives you a reference range. If the exact answer falls far outside that range, you know to check the setup, units, or arithmetic.

If 48% of 210 million should be roughly half of 200 million, you expect something near 100 million. An exact answer of 10 million should trigger a recheck.

Practice making a five-second magnitude estimate for larger calculations. If useful, this guide on case interview mental math gives more detail.